Steve Carell vuelve a encarnar a Evan Baxter, el acicalado presentador de Como Dios que descubre ser el siguiente elegido de Dios (Morgan Freeman) para llevar a cabo una misión sagrada. Evan, que acaba de ser elegido al Congreso, deja la ciudad de Búfalo y se traslada con su familia a Virginia del Norte. Una vez allí, su vida da un vuelco cuando se le aparece Dios y le ordena que construya un arca. Su aturdida esposa (Lauren Graham) y sus no menos sorprendidos hijos no acaban de decidir si Evan está pasando por una desproporcionada crisis de los cuarenta o si de verdad hay algo bíblico en todo esto.

Buffalo newsman Evan Baxter is elected to Congress with the slogan, "Change the world." He lucks into a huge house in a new Virginia suburb. His Capitol office is also fantastic, but there's a catch: he's tapped by the powerful Congressman Long to co-sponsor a bill to allow development in national parks. In steps God, who appears to a disbelieving Evan and gently commands him to build an ark. Tools and wood arrive in Evan's yard, animal pairs follow, his beard and hair grow wildly, nomad's clothes and a staff appear. Long grows impatient, Evan starts building, his family leaves him, reporters gather, and drought grips D.C. Still, Evan believes. But will he change the world?.