Nos cuenta la historia de un profesor de universidad que emplea su tiempo en dar clases y aconsejar a la Brigada de investigación criminal, cuando recibe una amenaza de muerte en la que le avisan que sólo le quedan 88 minutos de vida. El profesor tendrá que usar toda su habilidad para descubrir quién le amenaza y salvar así su vida. Entre los posibles sospechosos se encontrarán un estudiante disgustado, una antigua amante rechazada y un asesino en serie que está en el corredor de la muerte.

In Seattle, the successful forensic psychiatrist and college professor Jack Gramm is in evidence since he was responsible for the condemnation of the serial killer Jon Forster, influencing the jury to sentence him to the death row. Jon accuses Jack of manipulation, inducing one witness and sister of one of his victims to testify against him. On the eve of Jon's execution, Jack receives a phone call telling him that he has only eighty-eight minutes of life, while a killer is copycatting Jon, killing women with the same "modus-operandi" and is investigated by Seattle Slayer Task Force. With the support of associate Shelly Barnes, an FBI agent, his friend Frank Parks, and his assistant Kim Cummings, Jack investigates some weird and problematic students, a security guard of the campus and the woman with whom he had one night stand.