La exitosa autora Carrie Bradshaw (Sarah Jessica Parker), nuestro icono preferido de la moda, vuelve con su famoso ingenio totalmente intacto y más agudo que nunca, para narrarnos su propia historia sobre el sexo, el amor y la obsesión de las mujeres solteras de Nueva York por la moda. Sexo en Nueva York nos muestra a Carrie, a Samantha (Kim Cattrall), a Charlotte (Kristin Davis) y a Miranda (Cynthia Nixon) cuatro años después de que terminara la exitosa serie de HBO, y nos enseña cómo continúan haciendo juegos malabares para compaginar el trabajo y las relaciones mientras descubren los secretos de la maternidad, el matrimonio y las propiedades inmobiliarias de Manhattan.

After moving in together in an impossibly beautiful New York apartment, Carrie Bradshaw and Mr. Big make a rather arbitrary decision to get married. The wedding itself proves to be anything but a hasty affair--the guest list quickly blooms from 75 to 200 guests, and Carrie's simple, label-less wedding gown gives way to an enormous creation that makes her look like a gigantic cream puff. An upcoming photo spread in Vogue puts the event--which will take place at the New York Public Library--squarely in the public eye. Meanwhile, Carrie's girlfriends--Samantha, the sexpot; Charlotte, the sweet naïf; and Miranda, the rigid perfectionist--could not be happier. At least, they couldn't be happier for Carrie. Charlotte still has the unrealized hope of getting pregnant. Samantha is finding a loving, committed relationship more grueling than she could have imagined. Miranda unwittingly lets her own unhappiness--created when Steve admits to cheating on her just once--spoil Carrie's. After a heated encounter with Steve, she happens to spot Mr. Big and tells him he's crazy to get married. She's really only thinking of her own marriage. But her angry remark gets Mr. Big to thinking.